Hotels & Accommodation in Main Street Hyannis

your current months are January, 2025 and February, 2025.
January 2025
February 2025

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Where to stay in Main Street Hyannis?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Main Street Hyannis

Learn more about Main Street Hyannis

Main Street Hyannis is applauded for its cultural attractions such as John F. Kennedy Hyannis Museum and Cape Cod Baseball Hall of Fame. This beachside city's sights include Wackenhammer's Clockwork Arcade and visitors speak highly of the local seafood restaurants.

Frequently asked questions

Can I book a refundable accommodation option in Main Street Hyannis?
If you want the flexibility to change your plans to Main Street Hyannis, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Main Street Hyannis if I want a holiday rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 9 holiday homes.
What will the weather in Main Street Hyannis be like during my visit?
The warmest months in Main Street Hyannis are usually August and July, with an average temperature of 20°C. February and January are the chilliest months, when the average temperature is 3°C. The rainiest months are October and December.
Why should I book my Main Street Hyannis hotel with Hotels.com?
There are plenty of reasons to book your Main Street Hyannis travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.