If you're looking for a place to get away, look no further than Cairo. Whether you're planning to stay for a night or for the week, the area around Cairo has accommodation options to fit every need. Search for hotels in Cairo with Hotels.com by checking our online map. Our map displays the areas and neighbourhoods around all Cairo hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cairo hotel deals are here with our lowest price guarantee.
Hotels & Accommodation in Cairo
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Where to stay in Cairo?

Quality Inn Cairo I-57
Quality Inn Cairo I-57
6.6 out of 10, (260)
The price is R1 347
R1 495 total
includes taxes & fees
27 Jul - 28 Jul

Eagle Inn Charleston
Eagle Inn Charleston
6.8 out of 10, (100)
The price is R1 184
R1 314 total
includes taxes & fees
15 Jul - 16 Jul

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
6.6 out of 10, (572)
The price is R1 163
R1 290 total
includes taxes & fees
28 Jul - 29 Jul

Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
6.8 out of 10, (389)
The price is R1 245
R1 382 total
includes taxes & fees
28 Jul - 29 Jul

La Center Motel
La Center Motel
7.8 out of 10, Good, (14)
The price is R969
R1 133 total
includes taxes & fees
15 Jul - 16 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top landmarks in Cairo
Fort Defiance State Park
You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.
Learn more about Cairo
Cairo is well known for its attractions such as Mississippi River and Fort Defiance State Park.
Check out reviews of Cairo hotels guests love

Super 8 by Wyndham Charleston/Sikeston East MO
10/10 Excellent
Frequently asked questions
Find out more about Cairo
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