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Hotels & Accommodation in Melipilla

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Where to stay in Melipilla?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Melipilla on Hotels.com. These Melipilla hotels consistently deliver on quality, location and traveller experience. Last updated on 03 November 2026.

1. Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG
4.0 star property
Pudahuel
9.0 out of 10, Wonderful, (1 599 reviews)
Located within Santiago International Airport, this hotel welcomes travellers with an indoor pool and massage services. Grab a bite at the café or unwind at the bar after a day of travel. With ski shuttles and free WiFi, you're perfectly positioned for adventure.
The price is R3 572
R3 904 total
03 Dec - 04 Dec
Holiday Inn Santiago - Airport Terminal by IHG

2. Wyndham Santiago Aeropuerto

Wyndham Santiago Aeropuerto
4.5 star property
Pudahuel
9.2 out of 10, Wonderful, (1 513 reviews)
Escape jet lag at this Santiago sanctuary just minutes from the airport. Jump into the indoor pool or unwind at the spa after your flight. The 24-hour free shuttle, on-site restaurant, and bar ensure maximum convenience for travellers seeking rest.
The price is R1 744
R1 744 total
09 Nov - 10 Nov
Wyndham Santiago Aeropuerto

3. Courtyard by Marriott Santiago Airport

Courtyard by Marriott Santiago Airport
4.0 star property
Pudahuel
8.6 out of 10, Excellent, (769 reviews)
Unwind at this Santiago hotel, just minutes from the airport with convenient 24-hour shuttle service. Grab Mediterranean cuisine at Sabores restaurant or relax by the outdoor pool after a workout in the fitness centre. Free WiFi, parking, and breakfast add exceptional value.
The price is R1 980
R1 980 total
04 Dec - 05 Dec
Courtyard by Marriott Santiago Airport

4. Casona Lo Aguirre Hotel y Convenciones

Casona Lo Aguirre Hotel y Convenciones
4.0 star property
Talagante
10.0 out of 10, Exceptional, (3 reviews)
Escape to this colonial guesthouse with 2 outdoor pools and a winery in Talagante. Relax at the full-service spa, enjoy meals at the restaurant, or sip drinks at the poolside bar. Located near Casona Los Nogales, this retreat offers a fitness centre and free kids' club.
The price is R2 409
R3 239 total
15 Nov - 16 Nov
Casona Lo Aguirre Hotel y Convenciones

5. Hotel Boutique Lagunillas Casablanca

Hotel Boutique Lagunillas Casablanca
3.5 star property
Casablanca
9.4 out of 10, Exceptional, (51 reviews)
This colonial hotel in Casablanca offers wine enthusiasts a boutique escape with its own winery. Rejuvenate in the outdoor pool, hot tub, or sauna after exploring nearby Matetic Vineyard. Complimentary breakfast fuels adventures while the bar and café satisfy cravings.
The price is R4 037
R4 037 total
05 Nov - 06 Nov
Hotel Boutique Lagunillas Casablanca

6. Hotel Casa Real Viña Santa Rita

Hotel Casa Real Viña Santa Rita
4.0 star property
Buin
9.8 out of 10, Exceptional, (97 reviews)
Immerse yourself in Chilean wine culture at this Buin estate, complete with a winery for tasting local vintages. After exploring nearby Viña Santa Rita, unwind in the seasonal outdoor pool, sauna, or steam room before dining at the restaurant.
The price is R11 841
R11 841 total
15 Nov - 16 Nov
Hotel Casa Real Viña Santa Rita

7. City Express by Marriott Santiago Aeropuerto Chile

City Express by Marriott Santiago Aeropuerto Chile
3.0 star property
Pudahuel
8.6 out of 10, Excellent, (1 028 reviews)
This business-friendly haven offers 24-hour room service and free buffet breakfast just 10 minutes from Santiago Airport. Travellers praise the helpful staff while exploring nearby Templo Votivo de Maipu and Parque Quinta Normal with metro access.
The price is R1 725
R1 725 total
29 Nov - 30 Nov
City Express by Marriott Santiago Aeropuerto Chile

8. Hilton Garden Inn Santiago Airport

Hilton Garden Inn Santiago Airport
3.5 star property
Pudahuel
8.8 out of 10, Excellent, (1 003 reviews)
Santiago hotel with free airport shuttle sits close to cultural attractions like Parque Quinta Normal. Unwind in the indoor pool after skiing adventures, or recharge at the health club and fitness centre while enjoying drinks at the bar/lounge.
The price is R2 091
R2 091 total
04 Dec - 05 Dec
Hilton Garden Inn Santiago Airport

9. Hotel Casablanca Spa & Wine

Hotel Casablanca Spa & Wine
3.5 star property
Casablanca
7.4 out of 10, Good, (167 reviews)
Set in Chile's picturesque wine region near Veramonte and Bodegas RE, this hotel offers Italian cuisine alongside rejuvenating spa treatments. Enjoy the outdoor tennis court, fitness centre, and poolside bar after exploring nearby vineyards.
The price is R2 214
R2 214 total
09 Nov - 10 Nov
Hotel Casablanca Spa & Wine

10. Hotel Casino San Antonio by Enjoy

Hotel Casino San Antonio by Enjoy
3.5 star property
San Antonio
8.0 out of 10, Very good, (344 reviews)
Savour international cuisine at Ocean View restaurant while enjoying the Pacific breeze. This casino hotel offers complimentary breakfast, free WiFi, and attentive service, with Maípo River Wetland Park nearby for nature enthusiasts.
The price is R1 346
R1 346 total
11 Nov - 12 Nov
Hotel Casino San Antonio by Enjoy

11. Hotel Puerto Mayor

Hotel Puerto Mayor
3.0 star property
San Antonio
7.2 out of 10, Good, (40 reviews)
Savour the coastal charm at this San Antonio hotel, just a 5-minute walk from the bustling port. After exploring nearby Maípo River Wetland Park, unwind in the garden or sip drinks on the terrace. Free breakfast, WiFi, and parking enhance your stay.
The price is R1 340
R1 340 total
04 Nov - 05 Nov
Hotel Puerto Mayor

12. B&B Rocas Santo Domingo

B&B Rocas Santo Domingo
3.0 star property
Santo Domingo
9.8 out of 10, Exceptional, (28 reviews)
Wake up to ocean air at this Santo Domingo retreat near San Antonio Port. Free breakfast and WiFi set you up for adventure on nearby hiking trails. Relax with a drink at the bar after exploring, or prepare snacks in your room with the refrigerator and microwave.
The price is R2 076
R2 076 total
04 Nov - 05 Nov
B&B Rocas Santo Domingo

13. Nobile Hotel Estación Central

Nobile Hotel Estación Central
3.5 star property
Estación Central
8.8 out of 10, Excellent, (825 reviews)
This business-friendly hotel offers free WiFi and parking near Santiago Central Station. Grab a bite at the coffee shop or unwind with a drink at the bar while exploring nearby Costanera Centre and Parque Quinta Normal attractions.
The price is R817
R817 total
03 Dec - 04 Dec
Nobile Hotel Estación Central

14. Centro Turístico Cabañas Quirinal

Centro Turístico Cabañas Quirinal
2.5 star property
El Tabo
9.6 out of 10, Exceptional, (4 reviews)
Unwind at this El Tabo retreat featuring a sparkling outdoor pool and scenic terrace. Grab refreshments at the bar or café, then explore nearby Punta Lacho and El Peral Lagoon. Free WiFi and parking enhance your coastal adventure.
The price is R1 578
R1 578 total
05 Nov - 06 Nov
Centro Turístico Cabañas Quirinal

15. Hotel El Almendro

Hotel El Almendro
3.0 star property
Buin
8.0 out of 10, Very good, (7 reviews)
Immerse yourself in Chilean hospitality at this welcoming hotel offering free WiFi and daily breakfast. Just 8 minutes from Paine Station with 24-hour front desk service, it provides a convenient base for exploring the charming town of Buin.
The price is R2 456
R2 923 total
07 Nov - 08 Nov
Hotel El Almendro

16. Glamping Domos Lago rapel

Glamping Domos Lago rapel
1.0 star property
Las Cabras
The price is R1 217
R1 217 total
15 Nov - 16 Nov
Glamping Domos Lago rapel

17. Nobile Inn Santiago

Nobile Inn Santiago
3.0 star property
Estación Central
7.8 out of 10, Good, (892 reviews)
The price is R837
R837 total
16 Nov - 17 Nov
Nobile Inn Santiago

18. RQ Santiago

RQ Santiago
4.0 star property
Downtown Santiago
8.6 out of 10, Excellent, (647 reviews)
Centrally located in Santiago with La Moneda Station just steps away, this hotel offers free breakfast to start your day. Explore nearby attractions like Costanera Centre and Parque Arauco Mall, or enjoy the convenience of a 24-hour front desk.
The price is R1 069
R1 069 total
30 Nov - 01 Dec
RQ Santiago

19. General Bulnes 259

General Bulnes 259
3.5 star property
Downtown Santiago
8.4 out of 10, Very good, (5 reviews)
The price is R454
R1 387 total
04 Nov - 05 Nov
General Bulnes 259

20. Hotel Casa Aure

Hotel Casa Aure
3.0 star property
Downtown Santiago
9.0 out of 10, Wonderful, (116 reviews)
Feel the charm of Santiago from this cosy hotel, a short 7-minute walk from Cumming Station. Start your day with a complimentary cooked-to-order breakfast before exploring nearby Costanera Centre. Free WiFi and 24-hour reception ensure a convenient stay.
The price is R956
R956 total
03 Dec - 04 Dec
Hotel Casa Aure
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Go beyond your typical stay in Melipilla

Top landmarks in Melipilla

Learn more about Melipilla

Melipilla is well known for its attractions such as Vina Chocalan and Kartodromo Las Perdices.

A wooden house built on a tree stump with a steep roof and a tower.
Photo by Colour Of Sunshine
Open Photo by Colour Of Sunshine

Frequently Asked Questions

Can I book a refundable accommodation option in Melipilla?

If you want the flexibility to change your plans to Melipilla, most hotels offer refundable* rates that you can book. You can see this accommodation by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Melipilla if I want a holiday rental instead of a hotel?

If you want a good alternative to a hotel, browse our selection of 6 holiday homes.

What will the weather in Melipilla be like during my visit?

January and February are typically the warmest months in Melipilla, when the average temperature is 21°C. July and August are the coldest months, when the average temperature is 11°C. June and July are the months with the most rain.

Why should I book my Melipilla hotel with Hotels.com?

There are lots of reasons to book your Melipilla trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.