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All properties in Rome, Lazio, Italy
1 room, 2 adults

Twentyone Hotel

4-star4 stars
Via Cola di Rienzo 23, Rome, RM, 00192, Italy

4-star hotel with restaurant, near Piazza del Popolo
  • Free WiFi
  • Collect stampsYou can collect™ Rewards stamps here
  • The front desk staff are not very friendly and warm. Very cold and unhelpful. Will not…Dec 8, 2019
  • I would tell anyone and everyone that this is the best and most perfect hotel in Rome...…Aug 5, 2018

Twentyone Hotel

from ZAR 1,710
  • Double Room Single Use
  • Standard Double Room
  • Deluxe Double or Twin Room
  • Standard Triple Room
  • Standard Twin Room, 2 Twin Beds
  • Junior Suite

What’s around Twentyone Hotel


  • In Vatican
  • Piazza del Popolo - 7 min walk
  • Via del Corso - 8 min walk
  • Villa Borghese - 11 min walk
  • Castel Sant'Angelo - 12 min walk
  • Piazza di Spagna - 15 min walk
  • Piazza Navona - 15 min walk
  • Spanish Steps - 18 min walk

Getting around

  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO) - 34 min drive
  • Ciampino Airport (CIA) - 37 min drive
  • Rome Piazzale Flaminio Station - 11 min walk
  • Rome San Pietro Station - 29 min walk
  • Rome Euclide Station - 4 min drive
  • Lepanto Station - 8 min walk
  • Flaminio - Piazza del Popolo Station - 8 min walk
  • Ottaviano - San Pietro - Musei Vaticani Station - 14 min walk
  • Airport shuttle (surcharge)

At a glance

Key facts

Hotel size

  • This hotel has 86 rooms
  • This hotel is arranged over 8 floors


  • Check-in time 2 PM-midnight
  • Check-out time is 11 AM
  • Express check-in
Front desk staff will greet guests on arrival.
24-hour airport shuttle service is available on request. Fees may apply. Contact the property in advance to make arrangements.

Required at check-in

  • Credit card, debit card, or cash deposit required for incidental charges

  • Government-issued photo ID may be required

Travelling with others


  • One child stays free when occupying the parent or guardian's room, using existing bedding


  • Pets not allowed (service animals welcome)


  • Free WiFi and wired Internet access in public areas

  • Free WiFi and wired Internet access in rooms



  • Airport shuttle (available 24 hours) *


  • Self parking * on site

Payment types at the property

Other information

  • Smoke-free property
* See small print for additional details or extra charges

In the hotel

Food and drink
  • Buffet breakfast daily (surcharge)
  • Restaurant
  • Bar/lounge
  • Room service (during limited hours)
Things to do
  • Scooter/moped rentals nearby
Working away
  • Conference space
  • 24-hour front desk
  • Concierge services
  • Tours/ticket assistance
  • Limo or Town Car service available
  • Dry cleaning/laundry service
  • Laundry facilities
  • Luggage storage
  • Multilingual staff
  • Porter/bellhop
  • Year Built - 2009
  • Elevator
  • Garden
  • Television in common areas
  • Accessible bathroom
  • In-room accessibility
  • Roll-in shower
  • Wheelchair-accessible parking
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible on-site restaurant
  • Grab bar - near toilet
  • Bathroom emergency pull cord
Languages Spoken
  • English
  • French
  • German
  • Italian
  • Moldovan
  • Russian
  • Spanish

In the room

Home comforts
  • In-room climate control (air conditioning)
  • Minibar
  • Iron/ironing board (on request)
Sleep well
  • Premium bedding
Things to enjoy
  • Individually decorated
Freshen up
  • Private bathroom
  • Shower only
  • Bidet
  • Free toiletries
  • Hair dryer
Be entertained
  • Flat-screen TV
  • Pay movies
  • Premium TV channels
Stay connected
  • Desk
  • Free WiFi
  • Phone
  • Daily housekeeping
  • In-room safe

Twentyone Hotel’s small print

Also known as

  • Hotel Twentyone
  • Twentyone Hotel Hotel Rome
  • Twentyone Hotel
  • Twentyone Hotel Rome
  • Twentyone Rome
  • Twentyone Hotel Rome
  • Twentyone Hotel Rome
  • Twentyone Hotel Hotel


All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.

Cash transactions at this property cannot exceed EUR 1999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation.

Guests can rest easy knowing there's a fire extinguisher, a smoke detector, and a first aid kit on site.

This property advises that enhanced cleaning and guest safety measures are currently in place.

Disinfectant is used to clean the property; commonly-touched surfaces are cleaned with disinfectant between stays; bed sheets and towels are laundered at a temperature of at least 60°C/140°F.

Social distancing measures are in place; staff at the property wear personal protective equipment; a shield is in place between staff and guests in main contact areas; periodic temperature checks are conducted on staff; temperature checks are available to guests; guests are provided with hand sanitizer.

Contactless check-in is available.

Individually-wrapped food options are available for breakfast, lunch, and dinner, and also through room service.

For transfers, guests must contact the property before arrival at the number on the booking confirmation.

Mandatory fees

You’ll be asked to pay the following charges at check-in or check-out:

  • A tax is imposed by the city: EUR 6 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

Optional extras

Covered self parking costs EUR 25 per day with in/out privileges

Buffet breakfast is offered for an extra charge of EUR 8 per person (approximately)

Airport shuttle service is offered for an extra charge of EUR 65 per vehicle (one-way)

We have included all charges provided to us by this property. However, charges can vary, for example, based on length of stay or the unit you book.

FAQs for Twentyone Hotel

  • Does Twentyone Hotel offer free cancellation for a full refund?
    Yes, Twentyone Hotel does have fully refundable rooms available to book on our site, which can be cancelled up to a few days before check-in. Just make sure to check this property's cancellation policy for the exact terms and conditions.
  • What are the cleanliness and hygiene measures currently in place at Twentyone Hotel?
    This property confirms that disinfectant is used to clean the property. Furthermore, guests are provided with hand sanitizer, social distancing measures are in place, and staff wear personal protective equipment. Please note that this information has been provided by our partners.
  • Is parking offered on site at Twentyone Hotel?
    Yes. Self parking costs EUR 25 per day.
  • Are pets allowed at Twentyone Hotel?
    Sorry, pets aren't allowed, but service animals are welcome.
  • What are the check-in and check-out times at Twentyone Hotel?
    You can check in from 2 PM to midnight. Check-out time is 11 AM.
  • Are there restaurants at or near Twentyone Hotel?
    Yes, there's an onsite restaurant. Nearby restaurants include Brown & Co. (3-min walk), Su e Giù (4-min walk), and Miva (4-min walk).
  • Is airport shuttle service offered by Twentyone Hotel?
    Yes, an airport shuttle is available. The charge is EUR 65 per vehicle one-way.

Recent reviews

Very good 8,2 From 368 reviews

Exceptional 10,0
i have stayed here before. great staff, rooms clean and roomy, great location, few blocks from subway and price is good for what you receive
jay, ie1 night trip
Good 6,0
Great location, but lacking in services.
We have stayed at this hotel before and the location is great, but it is starting to look a little tired. For a 4 Star hotel I was also a bit disappointed with the facilities or lack of. There was no tea / coffee facilities within the room. The Hotel Bar shut at midnight, and bar staff were reluctant to give us glasses for drinks in our room. The Hotel is fine if your just looking for somewhere to crash after a day out exploring, but its not somewhere to spend any length of time at.
Thomas, gb5 night family trip
Fair 4,0
Amazing location, parking available but bad smell
Location is excellent, in a good neighborhood, walking distance to the historical center and to Vaticano. There is parking available per 25 euros a night. Unfortunately, there are some bad aspects related to this hotel: - the walls and windows are not soundproof, so it is possible to hear everything across the walls and from the street; - the bed is too hard, not comfort at all, and; - there is a strong smoking smell that comes from the bathroom.
Cristiane, us2 night family trip
Exceptional 10,0
Lovely hotel
Really good location and price, lovely hotel and staff were very helpful! Would recommend highly
Lucy, gb3 night trip
Very good 8,0
Close to Vatican city and city center. The breakfast was good and the room and decoration is quite elegant .
Lasse, us1 night romance trip
Exceptional 10,0
Great stay at Hotel 21
The location was safe, and convenient to restaurants, shops, attractions, and of course gelato. Our room was a good size as was the bathroom. It was quiet and comfortable for a nights rest after a long day of sightseeing. The staff was friendly and welcoming. I didn’t purchase the breakfast with the room, however we ate there a few days of our stay as it was convenient and there was a variety of food/drink choices. We always felt safe even walking around the neighborhood at any time of the day or night.
Sheila, us4 night family trip
Very good 8,0
The staff could have been more helpful
Maria, gb5 night romance trip
Good 6,0
Small room
Room with round bed definitely needs more room around the end to just get around, very difficult to do so. Also the room was smaller than the online pictures depicted. The best part of the stay, however, was the breakfast buffet, wonderful food and staff! Great city center location.
Amy, us2 night romance trip
Good 6,0
Not as expected
Hotel looked great online but was not as expected in person. The hotel was more rundown. The staff had some friendly people on it and others not so much. They did not go out of the way to help with anything. The room was smelly with dirty carpet and sheets that smelled. The location of the hotel was very nice and convenient.
us5 night trip with friends
Very good 8,0
Good area... Not to far from the Vatican
Love the hotel and the area... The room was a little warm and the bed was too firm... Only 1 pillow per person which usually you should have 2 per person... And please bring your own wash clothes because only towels and hand towels are given.
Shamian, us3 night romance trip

Twentyone Hotel

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