Hotels & Accommodation in Santo Tomé

your current months are January, 2025 and February, 2025.
January 2025
February 2025

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Where to stay in Santo Tomé?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santo Tomé

Learn more about Santo Tomé

Santo Tomé is well known for its attractions such as El Museo Etnografico y Colonial Juan de Garay and Museo De Arte Contemporaneo.

Frequently asked questions

Can I book a refundable accommodation option in Santo Tomé?
If you want the flexibility to change your plans to Santo Tomé, most hotels offer refundable* rates that you can book. You can see this accommodation by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santo Tomé be like during my visit?
The warmest months in Santo Tomé are usually January and December, with an average temperature of 25°C. July and June are the chilliest months, when the average temperature is 14°C. The rainiest months are February and December.
Why should I book my Santo Tomé hotel with Hotels.com?
There are plenty of reasons to book your Santo Tomé travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.