Hotels & Accommodation in Seneca

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Check prices for these dates

Tonight
08 Oct - 09 Oct
Tomorrow
09 Oct - 10 Oct
This weekend
09 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Where to stay in Seneca?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Seneca on Hotels.com. These Seneca hotels consistently deliver on quality, location and traveller experience. Last updated on .

A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R1 995
R2 195 total
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A reception area with a counter, chairs, and a patterned rug.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R1 978
R2 176 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Seneca-Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A food court with a beverage display, seating area, and a Clemson University sign.

3. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R1 773
R1 950 total
includes taxes & fees
18 Oct - 19 Oct
Tru by Hilton Seneca Clemson
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

4. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 682
R1 851 total
includes taxes & fees
11 Oct - 12 Oct
Best Western Seneca-Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

5. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 803
R2 238 total
includes taxes & fees
18 Oct - 19 Oct
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

6. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 257
R1 483 total
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Seneca US-123
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A Days Inn reception area with a view of the parking lot and trees.

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 373
R1 510 total
includes taxes & fees
11 Oct - 12 Oct
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
Private kitchen
A wooden interior with a table, chair, and a hanging lantern.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R1 532
R2 413 total
includes taxes & fees
28 Oct - 29 Oct
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A golf course with a water body, trees, and a distant view of a bridge.
A golf course with a clubhouse, surrounded by dense trees and a large body of water.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

9. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
R2 465
R2 736 total
includes taxes & fees
14 Oct - 15 Oct
Clemson University's James F. Martin Inn
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
An outdoor patio with wicker furniture, a round table, and a fountain.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

10. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
R3 457
R3 837 total
includes taxes & fees
13 Oct - 14 Oct
The Shepherd Hotel Downtown Clemson
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.
A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.
A modern living room with a flat-screen TV, a desk with a chair, an orange sofa, and a framed tiger picture on the wall.
A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

11. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
Clemson
R2 146
R2 382 total
includes taxes & fees
09 Oct - 10 Oct
Holiday Inn Express & Suites Clemson by IHG
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

12. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
R2 665
R2 958 total
includes taxes & fees
18 Oct - 19 Oct
The Abernathy of Clemson
A modern kitchen area with a bar counter and seating.
A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.
A modern bar area with high stools and a poolside view.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

13. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
R1 814
R2 013 total
includes taxes & fees
14 Oct - 15 Oct
Hampton Inn Clemson-University Area
Room
A spacious room with a large window, a flat-screen TV mounted on the wall, and a seating area with sofas and chairs.
A hotel reception area with two reception desks, a digital screen, and a tiled floor.
A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

14. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
R1 753
R1 946 total
includes taxes & fees
01 Nov - 02 Nov
Comfort Inn & Suites Clemson - University Area
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.
A lobby with seating areas, a reception desk, and a patterned wall.
A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

15. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
R1 743
R1 935 total
includes taxes & fees
14 Oct - 15 Oct
Best Western Plus Clemson Hotel & Conference Center
A modern bar area with a menu board, bar stools, and a countertop with various items.
An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.
A modern dining area with a bar, bar stools, and a patterned rug.
A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

16. Courtyard Marriott Clemson

Courtyard Marriott Clemson
Clemson
R1 783
R1 979 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard Marriott Clemson
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.
A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.
A brick building with a sign reading "The Inn at Patrick Square".
A hotel lobby with a long corridor, seating areas, and a reception desk.

17. The Inn at Patrick Square

The Inn at Patrick Square
Clemson
R2 465
R2 736 total
includes taxes & fees
11 Oct - 12 Oct
The Inn at Patrick Square
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A wall with a decorative design featuring a building, trees, and a sky with clouds.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

18. Inn @ Clemson

Inn @ Clemson
Clemson
R1 472
R1 634 total
includes taxes & fees
11 Oct - 12 Oct
Inn @ Clemson
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.
A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.
A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.
A reception desk with a vase of flowers, framed pictures, and a printer.

19. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
Clemson
R1 325
R1 471 total
includes taxes & fees
09 Oct - 10 Oct
Days Inn by Wyndham Clemson
A kitchen with a coffee maker, microwave, and refrigerator.
A red brick building with a white porch and columns, a door, and windows.
A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.
A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.

20. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
Walhalla
R1 202
R1 340 total
includes taxes & fees
07 Nov - 08 Nov
Rodeway Inn & Suites Walhalla
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A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R2 312
per night
R2 543 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R2 312
per night
R2 543 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 563
per night
R1 829 total
includes taxes & fees
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 979
per night
R2 177 total
includes taxes & fees
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A Days Inn reception area with a view of the parking lot and trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 497
per night
R1 647 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R2 312
per night
R2 543 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 979
per night
R2 442 total
includes taxes & fees
Lakeside Lodge Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
Private kitchen
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R1 896
per night
R2 818 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R2 312
per night
R2 543 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 730
per night
R2 017 total
includes taxes & fees
Quality Inn Seneca US-123
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R2 661
per night
R2 927 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R2 062
per night
R2 269 total
includes taxes & fees
Best Western Seneca-Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 813
per night
R2 251 total
includes taxes & fees
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A Days Inn reception area with a view of the parking lot and trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 364
per night
R1 500 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R2 312
per night
R2 543 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
Private kitchen
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R3 643
per night
R4 739 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Check out pet-friendly hotels in Seneca

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 803
R2 238 total
includes taxes & fees
18 Oct - 19 Oct
Lakeside Lodge Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R1 773
R1 950 total
includes taxes & fees
18 Oct - 19 Oct
Tru by Hilton Seneca Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 257
R1 483 total
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Seneca US-123
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A Days Inn reception area with a view of the parking lot and trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 373
R1 510 total
includes taxes & fees
11 Oct - 12 Oct
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
Private kitchen
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R1 532
R2 413 total
includes taxes & fees
28 Oct - 29 Oct
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
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You can also stay at hotels with a pool in Seneca

A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R1 995
R2 195 total
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R1 978
R2 176 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Seneca-Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 803
R2 238 total
includes taxes & fees
18 Oct - 19 Oct
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 257
R1 483 total
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 682
R1 851 total
includes taxes & fees
11 Oct - 12 Oct
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A Days Inn reception area with a view of the parking lot and trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 373
R1 510 total
includes taxes & fees
11 Oct - 12 Oct
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveller single night rates
View properties in October
Typical weather for Seneca
October
High 23°C / low 12°C. Sunny most days.
View properties in October
23°
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17°
6°
12°
4°
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1°
13°
3°
17°
6°
22°
10°
26°
15°
31°
19°
32°
21°
31°
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18°
Monthly weather averages (˚C)

Top neighbourhoods in Seneca

A lakeside scene with autumn foliage, a clear sky, and a sunset.
A large lake surrounded by dense forests.

Downtown

Seneca's Downtown neighbourhood has lots of places to visit, such as Oconee County Library Seneca Branch and Blue Ridge Arts Center.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Seneca's Serenity Bay neighbourhood offers attractions, including Lake Keowee.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

Seneca's Pine Ridge Point neighbourhood offers attractions, including Lake Keowee.

Indian Oaks

Seneca's Indian Oaks neighbourhood offers attractions, including Lake Keowee.

Top landmarks in Seneca

A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
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A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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Toy Train Park

Toy Train Park is worth a pic or two when discovering Downtown.
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Highpointe Field

Highpointe Field is worth a visit, located 5.6 mi (8.9 km) from central Seneca.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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World of Energy

If museums are on your list of things to see in Seneca, then you might want to head to World of Energy. If you want to experience more of the culture Seneca has to offer, head to Lake Keowee, Keowee Key Golf Course, and High Falls County Park.
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Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic city centre offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

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A sunset over a lake surrounded by dense forests and residential areas.

Check out reviews of Seneca hotels guests love

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent
"Great stay!"
Melissa 1-night trip
Posted 1 hour ago
Tru by Hilton Seneca Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

10/10 Excellent
"Convenient location for doing business in seneca, and parts of clemson. The staff was wonderful. The breakfast was great."
Lori 1-night trip
Posted 1 day ago
Fairfield Inn & Suites Seneca Clemson Univ Area
Quality Inn Seneca US-123

Quality Inn Seneca US-123

8/10 Good
"Second time here! Staff great! This time my room smelled of smoke as a non smoking room! Comforter was clean but from a smoking room and smelled despite it being clean!"
Gina 2-night trip
Posted 3 days ago
Quality Inn Seneca US-123
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"Great place to stay when visiting Clemson!"
Lloyd 1-night trip
Posted 6 days ago
Hampton Inn & Suites Seneca-Clemson Area
Best Western Seneca-Clemson

Best Western Seneca-Clemson

8/10 Good
"Stayed @ hotel for a football weekend. Hotel was awesome...one of the cleanest I've ever stayed in regardless of hotels' star ratings. The only reason I gave it 4 stars was two things....#1 The bed was a bit too hard for me. I'm used to softer mattresses, but these were a little too hard for me. #2....There was one staff person that was just not very friendly @ the front desk for part of my stay. She wasn't rude & she fulfilled my requests, but she just was not as outgoing as other team members & that stuck out to me. Would I stay at this hotel again? Absolutely...it's been many yrs since I've stayed in a BW...I tend to stay in the upper crust hotels, so I was very pleasantly surprised! Great job Best Western!!"
Susan 2-night trip
Posted 7 days ago
Best Western Seneca-Clemson

Frequently asked questions

Can I book a refundable accommodation option in Seneca?
If you want the flexibility to change your plans to Seneca, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 217 holiday homes. In addition, there are 24 apartments and 13 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 8°C. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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