Hotels & Accommodation in Seneca

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Tonight
28 Aug - 29 Aug
Tomorrow
29 Aug - 30 Aug
This weekend
28 Aug - 30 Aug
Next weekend
04 Sept - 06 Sept

Top 5 hotels in Seneca at a glance

  1. Tru by Hilton Seneca Clemson — 2.5-star hotel in Seneca. Guest rating: 9,2/10 — Wonderful.
  2. Fairfield Inn & Suites Seneca Clemson Univ Area — 3-star hotel in Seneca. Guest rating: 9,4/10 — Exceptional.
  3. Quality Inn Seneca US-123 — 2.5-star hotel in Seneca. Guest rating: 8,0/10 — Very good.
  4. Best Western Seneca-Clemson — 2.5-star hotel in Seneca. Guest rating: 8,4/10 — Very good.
  5. Days Inn by Wyndham Seneca / Clemson Area — 2-star hotel in Seneca. Guest rating: 6,8/10.

Where to stay in Seneca?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Seneca on Hotels.com. These Seneca hotels consistently deliver on comfort, location and traveller experience. Last updated on .

An outdoor patio area with a fire pit, seating, and string lights.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R1 692
R1 861 total
includes taxes & fees
13 Sept - 14 Sept
Tru by Hilton Seneca Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R1 919
R2 111 total
includes taxes & fees
06 Sept - 07 Sept
Fairfield Inn & Suites Seneca Clemson Univ Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 209
R1 426 total
includes taxes & fees
03 Sept - 04 Sept
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 550
R1 705 total
includes taxes & fees
30 Aug - 31 Aug
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A Days Inn reception area with a view of a parking lot and a grassy area.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 296
R1 425 total
includes taxes & fees
30 Aug - 31 Aug
Days Inn by Wyndham Seneca / Clemson Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R1 898
R2 088 total
includes taxes & fees
03 Sept - 04 Sept
Hampton Inn & Suites Seneca-Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 743
R2 164 total
includes taxes & fees
29 Aug - 30 Aug
Lakeside Lodge Clemson
A cabin with a large window, surrounded by trees.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R1 482
R2 334 total
includes taxes & fees
02 Sept - 03 Sept
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
An outdoor patio with wicker furniture, a round table, and a fountain.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
R3 823
R4 243 total
includes taxes & fees
29 Aug - 30 Aug
The Shepherd Hotel Downtown Clemson
A modern kitchen area with a bar counter and seating.
A vending area with snacks and beverages, including chips and soda.
A modern bar area with high stools and a poolside view.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
R1 692
R1 878 total
includes taxes & fees
06 Sept - 07 Sept
Hampton Inn Clemson-University Area
A modern kitchen with a microwave, coffee maker, and bar stools.
A Comfort Inn & Suites hotel with a modern design, featuring a prominent sign, well-maintained landscaping, and a clear view of the entrance.
A hotel lobby with a reception desk, a large tiger mural, a TV, and a seating area with a blue sofa.
A hotel room with a large flat-screen TV mounted on the wall, a desk with a chair, a bedside table, a lamp, and a wardrobe.

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
R1 686
R1 871 total
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn & Suites Clemson - University Area
A golf course with a water body, trees, and a distant view of a bridge.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.
A modern building with a central entrance, surrounded by a well-maintained lawn and trees.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
R2 383
R2 645 total
includes taxes & fees
01 Sept - 02 Sept
Clemson University's James F. Martin Inn
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.
A lobby with seating areas, a reception desk, and a patterned wall.
A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
R1 618
R1 796 total
includes taxes & fees
30 Aug - 31 Aug
Best Western Plus Clemson Hotel & Conference Center
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.
A hotel room with two beds, a desk, a television, and a clock on the wall.

Inn @ Clemson

Inn @ Clemson
Clemson
R1 424
R1 580 total
includes taxes & fees
29 Aug - 30 Aug
Inn @ Clemson
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.
A brick building with a sign reading "The Inn at Patrick Square".
A hotel lobby with a long corridor, seating areas, and a reception desk.
A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.

The Inn at Patrick Square

The Inn at Patrick Square
Clemson
R2 383
R2 645 total
includes taxes & fees
30 Aug - 31 Aug
The Inn at Patrick Square
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

The Abernathy of Clemson

The Abernathy of Clemson
Clemson
R2 703
R3 001 total
includes taxes & fees
02 Sept - 03 Sept
The Abernathy of Clemson
A poolside area with wicker furniture and a table, surrounded by a fence and greenery.
A Fairfield by Marriott hotel with a modern design, featuring a covered entrance, multiple floors, and a well-lit facade.
A modern living room with a stone wall, a fireplace, and a large window. There are two sofas, a coffee table, and a dining area with a table and chairs.
A corner market with a wooden interior, a glass door entrance, and a refrigerator display.

Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
Anderson
R1 482
R1 645 total
includes taxes & fees
06 Sept - 07 Sept
Fairfield Inn & Suites by Marriott Anderson Clemson
A modern living room with a sectional sofa, a coffee table, a fireplace, and a clock on the wall.
A spacious lobby with a reception desk, seating area, and a patterned rug.
A hotel room with a green sofa, a small table, a brown armchair, a bed with a red blanket, and a television on a wooden stand.
A kitchen area with blue cabinets, a countertop with various food items, and overhead lighting.

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
Anderson
R1 550
R1 720 total
includes taxes & fees
20 Sept - 21 Sept
Country Inn & Suites by Radisson, Anderson, SC
A kitchen with a coffee maker, microwave, and refrigerator.
A red brick building with a white porch and columns, a door, and windows.
A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.
A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
Walhalla
R1 223
R1 364 total
includes taxes & fees
27 Sept - 28 Sept
Rodeway Inn & Suites Walhalla
A patio area with a round table and chairs, a fire pit, and a building with a stone facade and blue accents.
A modern building with a swimming pool, stone facade, and blue lounge chairs.
A modern hotel lobby with a long communal table, seating areas, and a TV mounted on the wall.
A modern hotel lobby with a reception desk, seating area, and a large chandelier.

Residence Inn by Marriott Anderson Clemson

Residence Inn by Marriott Anderson Clemson
Anderson
R2 287
R2 539 total
includes taxes & fees
06 Sept - 07 Sept
Residence Inn by Marriott Anderson Clemson
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A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 424
per night
R1 669 total
includes taxes & fees
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 743
per night
R2 164 total
includes taxes & fees
Lakeside Lodge Clemson
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 823
per night
R2 006 total
includes taxes & fees
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R2 223
per night
R2 446 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A Days Inn reception area with a view of a parking lot and a grassy area.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 360
per night
R1 496 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R2 431
per night
R2 674 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R2 383
per night
R2 622 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A cabin with a large window, surrounded by trees.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R2 703
per night
R3 677 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 424
per night
R1 669 total
includes taxes & fees
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 743
per night
R2 164 total
includes taxes & fees
Lakeside Lodge Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R2 223
per night
R2 446 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 823
per night
R2 006 total
includes taxes & fees
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R2 223
per night
R2 446 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A Days Inn reception area with a view of a parking lot and a grassy area.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 360
per night
R1 496 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R2 383
per night
R2 622 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A cabin with a large window, surrounded by trees.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R2 863
per night
R3 853 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
An outdoor patio area with a fire pit, seating, and string lights.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R1 823
per night
R4 011 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 353
per night
R3 178 total
includes taxes & fees
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 754
per night
R3 858 total
includes taxes & fees
Best Western Seneca-Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R2 068
per night
R4 549 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 903
per night
R4 696 total
includes taxes & fees
Lakeside Lodge Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R2 383
per night
R5 243 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A Days Inn reception area with a view of a parking lot and a grassy area.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 464
per night
R3 220 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a large window, surrounded by trees.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R1 027 off
R2 909
per night
R7 808 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A clear lake with a rocky shoreline and a tree branch overhanging the water.
A grassy area with trees and a body of water.
A two-story building with a garage, a staircase, and a view of the water.
A wooden deck with a view of a forested area and a building with a sloped roof.

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

6 Mi to South Cove Boat Ramp! Lake Keowee Escape
Seneca
R3 439
per night
R11 268 total
includes taxes & fees
6 Mi to South Cove Boat Ramp! Lake Keowee Escape
A round wooden table with a flower vase and a WiFi sign, surrounded by blue cushioned benches, in a room with large windows and a hanging light fixture.
A covered porch with a flag, a tree, and a house entrance.
A covered porch with a ceiling fan, a wooden bench, a cushioned sofa, and a small table.

Screened Patio & Yard: Clemson Weekends/lakes Stay

Screened Patio & Yard: Clemson Weekends/lakes Stay
Seneca
R3 871
per night
R13 358 total
includes taxes & fees
Screened Patio & Yard: Clemson Weekends/lakes Stay
A living room with a flat-screen TV, wooden entertainment unit, and a ceiling fan.
A modern kitchen with stainless steel appliances, wooden cabinets, and a granite countertop.
A modern kitchen with stainless steel appliances, wooden cabinets, granite countertops, and a built-in oven.
A multi-story residential building with a parking lot in front.

Condo on Lake Hartwell 3 Mi to Clemson Stadium

Condo on Lake Hartwell 3 Mi to Clemson Stadium
Seneca
R3 575
per night
R11 631 total
includes taxes & fees
Condo on Lake Hartwell 3 Mi to Clemson Stadium
A wooden deck with a metal roof, overlooking a lake and houses.
A kitchen with a wooden table, white cabinets, a microwave, a coffee maker, and a sink.
A modern multi-story building with a wooden staircase leading up to a balcony, surrounded by trees.
A wooden bridge leading to a house with a view of a lake.

Lake Keowee Gem! Close to Clemson & Hiking Trails

Lake Keowee Gem! Close to Clemson & Hiking Trails
Seneca
R10 021
per night
R26 243 total
includes taxes & fees
Lake Keowee Gem! Close to Clemson & Hiking Trails
A covered patio with wooden chairs and a table, overlooking a fenced yard with a body of water and trees.
A two-story house with a dark roof, a garage, and a large rock in the foreground.
A house with a pathway leading to a dock, surrounded by trees and a body of water.
A spacious living area with a sofa set, a glass coffee table, and a ceiling fan.

Lakefront Seneca Vacation Rental w/ Shared Dock!

Lakefront Seneca Vacation Rental w/ Shared Dock!
Seneca
R6 318
per night
R17 128 total
includes taxes & fees
Lakefront Seneca Vacation Rental w/ Shared Dock!

Check out pet-friendly hotels in Seneca

An outdoor patio area with a fire pit, seating, and string lights.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
R1 692
R1 861 total
includes taxes & fees
13 Sept - 14 Sept
Tru by Hilton Seneca Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 209
R1 426 total
includes taxes & fees
03 Sept - 04 Sept
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 743
R2 164 total
includes taxes & fees
29 Aug - 30 Aug
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A Days Inn reception area with a view of a parking lot and a grassy area.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 296
R1 425 total
includes taxes & fees
30 Aug - 31 Aug
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a large window, surrounded by trees.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
R1 482
R2 334 total
includes taxes & fees
02 Sept - 03 Sept
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
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You may also like hotels with pools in Seneca

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
R1 743
R2 164 total
includes taxes & fees
29 Aug - 30 Aug
Lakeside Lodge Clemson
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
R1 550
R1 705 total
includes taxes & fees
30 Aug - 31 Aug
Best Western Seneca-Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
R1 209
R1 426 total
includes taxes & fees
03 Sept - 04 Sept
Quality Inn Seneca US-123
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
R1 898
R2 088 total
includes taxes & fees
03 Sept - 04 Sept
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
R1 919
R2 111 total
includes taxes & fees
06 Sept - 07 Sept
Fairfield Inn & Suites Seneca Clemson Univ Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A Days Inn reception area with a view of a parking lot and a grassy area.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
R1 296
R1 425 total
includes taxes & fees
30 Aug - 31 Aug
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveller single night rates
View properties in August
Typical weather for Seneca
August
High 31°C / low 20°C. Sunny most days.
View properties in August
31°
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12°
17°
6°
12°
4°
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1°
13°
3°
17°
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22°
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15°
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Monthly weather averages (˚C)

Top neighbourhoods in Seneca

A large lake surrounded by dense forests.
A lakeside scene with autumn foliage, a clear sky, and a sunset.

Downtown

Seneca's Downtown neighbourhood has lots of places to visit, such as Oconee County Library Seneca Branch and Blue Ridge Arts Center.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Seneca's Serenity Bay neighbourhood offers attractions, including Lake Keowee.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

Seneca's Pine Ridge Point neighbourhood offers attractions, including Lake Keowee.

Indian Oaks

Seneca's Indian Oaks neighbourhood offers attractions, including Lake Keowee.

Top landmarks in Seneca

A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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Seneca City Hall

Seneca City Hall is worth a pic or two when discovering Downtown.
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Highpointe Lower Field

Highpointe Lower Field is worth a visit, located 5.7 mi (9.1 km) from central Seneca.
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The Gauntlet

If you want to see a show while you're in town, try and grab some tickets at The Gauntlet in Downtown. If you enjoy the show and want to see another, Oconee Community Theatre isn't far.
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Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic city centre offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

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A calm lake with mountains in the background.

Check out reviews of Seneca hotels guests love

Quality Inn Seneca US-123

Quality Inn Seneca US-123

10/10 Excellent
"Convenient location. Reasonably priced. Staff is very friendly and helpful."
Kwanchanok 1-night trip
Posted 1 day ago
Quality Inn Seneca US-123

Frequently asked questions

Can I book a refundable accommodation option in Seneca?
If you want the flexibility to change your plans to Seneca, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 218 holiday homes. In addition, there are 21 apartments and 12 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 8°C. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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