Hotels & Accommodation in Panacea

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
17 Sept - 18 Sept
Tomorrow
18 Sept - 19 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Where to stay in Panacea?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Panacea on Hotels.com. These Panacea hotels consistently deliver on quality, location and traveller experience. Last updated on .

1. The Panacea Motel

The Panacea Motel
Panacea
R1 953
R2 177 total
includes taxes & fees
21 Sept - 22 Sept
The Panacea Motel

2. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
R1 823
R2 032 total
includes taxes & fees
11 Oct - 12 Oct
Best Western Wakulla Inn & Suites

3. Wildwood Inn

Wildwood Inn
Crawfordville
R1 901
R2 185 total
includes taxes & fees
11 Oct - 12 Oct
Wildwood Inn

4. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
R2 077
R2 912 total
includes taxes & fees
20 Sept - 21 Sept
St James Bay Golf & Pickleball Resort

5. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
R1 463
R1 631 total
includes taxes & fees
27 Sept - 28 Sept
The Lodge at Wakulla Springs

6. Franklin Inn

Franklin Inn
Carrabelle
R1 713
R1 892 total
includes taxes & fees
20 Sept - 21 Sept
Franklin Inn

7. The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
R1 903
R2 103 total
includes taxes & fees
01 Oct - 02 Oct
The Old Carrabelle Hotel

8. The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
R2 262
R2 499 total
includes taxes & fees
01 Oct - 02 Oct
The Moorings Hotel and Marina
View all properties
Our prices for hotels in Panacea are cheapest in February
Price trends for hotels in Panacea
Pricing is based on two traveller single night rates
View properties in September
Typical weather for Panacea
September
High 30°C / low 23°C. Sunny most days.
View properties in September
30°
23°
27°
18°
22°
13°
19°
11°
17°
19°
10°
22°
13°
25°
16°
29°
20°
31°
23°
32°
24°
32°
25°
Monthly weather averages (˚C)

Top landmarks in Panacea

Alligator Point Beach

8.8/10 (10 reviews)
When the beach is calling your name, you might want to head down to Alligator Point Beach, located 4.5 mi (7.2 km) from central Alligator Point. Enjoy the sunset by the shore at Wilson Beach.
See properties

Bald Point State Park

8.6/10 (20 reviews)
Bald Point State Park is 1.7 mi (2.7 km) from central Alligator Point, why not stop by during your stay?
See properties

Mashes Sand Beach

8.8/10 (3 reviews)
If being by the water is a major draw, Mashes Sand Beach is a spot you might want to check out, located 5.1 mi (8.2 km) from central Panacea. If you want to continue walking by the waves, head to Shell Point Beach, Alligator Point Beach and Wilson Beach.
See properties

Wilson Beach

Whether you want to collect beach glass or watch the sunset, Wilson Beach is a spot you might want to check out, located 7.4 mi (11.9 km) from central Panacea. Enjoy the sunset by the shore at Alligator Point Beach.
See properties

beach near Alligator Point

When the beach is calling your name, you might want to head down to beach near Alligator Point, located 2.7 mi (4.4 km) from central Alligator Point. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
See properties

beach near Summer Camp Beach

Whether you want to collect beach glass or watch the sunset, beach near Summer Camp Beach is a spot you might want to check out, located 10.3 mi (16.6 km) from central Panacea. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
See properties

Public Beach Access

Public Beach Access is 2.3 mi (3.7 km) from central Alligator Point, why not stop by during your stay? Want to stretch your legs a little more? Head to Alligator Harbor Aquatic Preserve, located nearby.
See properties

beach near Alligator Point Marina

When the beach is calling your name, you might want to head down to beach near Alligator Point Marina, located 3 mi (4.8 km) from central Alligator Point. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
See properties

Learn more about Panacea

Notable for its natural beauty, Panacea features attractions such as Mashes Sand Beach and Alligator Point Beach. This beachside city has something for everyone including seafood restaurants and sights like Bald Point State Park and Wilson Beach—all within a secluded setting.

See all hotels in Panacea
A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Check out reviews of Panacea hotels guests love

The Panacea Motel

The Panacea Motel

10/10 Excellent
"Our room was nicely decorated in a Coastal theme, clean, very comfortable bed, amenities available in room. Coffee pot, mini-fridge, microwave, TV, AC. Quiet and private, slept very well, and must mention, the water pressure is excellent! Makes for a great shower! Suggestion brochures avail for things to do in the area. Will definitely stay again. Love the area."
Allison 1-night trip
Posted 11 days ago
The Panacea Motel

Frequently asked questions

Can I book a refundable accommodation option in Panacea?
If you want the flexibility to change your plans to Panacea, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Panacea if I want a holiday rental instead of a hotel?
If you're looking for a good alternative to a hotel, browse our selection of 175 holiday homes. In addition, there are 18 apartments and 10 condos.
What will the weather in Panacea be like during my visit?
July and August are typically the warmest months in Panacea, when the average temperature is 27°C. January and February are the coldest months, when the average temperature is 14°C. August and July are the months with the most rain.
Why should I book my Panacea hotel with Hotels.com?
There are lots of reasons to book your Panacea trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Keep exploring