Hotels & Accommodation in Santa Cruz

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
18 Oct - 19 Oct
Tomorrow
19 Oct - 20 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 01 Nov

Where to stay in Santa Cruz?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Santa Cruz on Hotels.com. These Santa Cruz hotels consistently deliver on quality, location and traveller experience. Last updated on .

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.
A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.
A buffet with various fruits and snacks.
A sauna with wooden walls and benches.

1. Hotel Cortez

Hotel Cortez
Equipetrol
R2 135
R2 135 total
23 Oct - 24 Oct
Hotel Cortez
A poolside area with lounge chairs and a palm tree.
A pathway through a lush garden with various trees and shrubs.
A dining table with breakfast items and a pool view.
A banquet hall with long tables, chandeliers, and draped curtains.

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Equipetrol
R2 227
R2 227 total
07 Nov - 08 Nov
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.
A traditional-style room with a sofa set, a table, and two chairs.
A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.
Wicker furniture with cushions, potted plants, and a ceiling with lights.

3. Lido Hotel

Lido Hotel
Centro Histórico
R420
R420 total
20 Oct - 21 Oct
Lido Hotel
A modern lobby with seating areas, a coffee table, and a large potted plant.
A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.
A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.
A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

4. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
Equipetrol
R690
R690 total
24 Oct - 25 Oct
Ibis Santa Cruz DE LA Sierra
A hotel with a large swimming pool, multiple balconies, and a central arched entrance.
A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.
A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.
A table set for a meal with a view of a body of water and decorative lighting.

5. Sun Hotel

Sun Hotel
Santa Cruz
R1 780
R1 780 total
19 Oct - 20 Oct
Sun Hotel
A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.
A spacious lobby with high ceilings, large windows, and a modern chandelier.
A restaurant with a long counter, dark chairs, and hanging lights.
An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

6. Camino Real Hotel

Camino Real Hotel
Santa Cruz
R2 870
R2 870 total
30 Oct - 31 Oct
Camino Real Hotel
A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".
A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.
An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.
A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

7. Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
Equipetrol
R1 796
R1 796 total
30 Oct - 31 Oct
Alfonsina Hotel Boutique by Inboccaluppo
A modern hotel room with a bed, sofa, ottoman, TV, and a painting of a lion.
A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.
A rooftop pool area with a view of the city skyline at dusk.
A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

8. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
Equipetrol
R1 796
R1 796 total
01 Nov - 02 Nov
TRYP by Wyndham Santa Cruz
A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.
A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.
A modern hotel building with a glass facade, a prominent sign for 'OSHO HOTEL', and a logo with a stylized building and tree.
A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

9. HOTEL OSHO

HOTEL OSHO
Santa Cruz
R832
R832 total
15 Nov - 16 Nov
HOTEL OSHO
A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.
A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.
A small, enclosed garden area with various potted plants and a gravel path.
A hotel with a prominent 'Hampton' sign, large windows, and a modern facade.

10. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Santa Cruz
R1 213
R1 213 total
29 Oct - 30 Oct
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
A hotel room with a bed, a desk with a chair, a television, and a window with a city view.
A corridor with tiled flooring, potted plants, and a view of a building with a thatched roof.
A gym with various exercise equipment, including a treadmill, weight machines, and a bench.
A lobby with a marble floor, an elevator, and a view of the outdoor seating area.

11. Gran Hotel Santa Cruz

Gran Hotel Santa Cruz
Centro Histórico
R961
R961 total
19 Oct - 20 Oct
Gran Hotel Santa Cruz
A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.
A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.
A modern lobby with a dining area, sofas, and a decorative wall.
A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

12. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
Santa Cruz
R1 743
R1 743 total
01 Nov - 02 Nov
Marriott Santa Cruz de la Sierra Hotel
A hotel room with two beds, a desk, a chair, a television, and a window with curtains.
A café area with a staircase, a sofa, and tables with chairs.
A wooden door with a notice and a small bedside table with a lamp.
A reception desk with a wooden finish, a framed wildlife painting, and a green leaf-patterned wall mural.

13. Gran Hotel Mediterráneo

Gran Hotel Mediterráneo
Centro Histórico
R901
R901 total
19 Oct - 20 Oct
Gran Hotel Mediterráneo
A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.
A modern lobby with wooden paneling, two grey sofas, and pendant lighting.
A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.
A modern staircase with glass railings, leading to a landing with a small garden area.

14. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
Santa Cruz
R758
R758 total
20 Oct - 21 Oct
Premium Suites Deluxe Aparthotel Equipetrol
A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.
A building with a sign that reads "COSMOPOLITANO."
A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.
A multi-level indoor space with a pool, wooden flooring, and potted plants.

15. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
Centro Histórico
R871
R871 total
16 Nov - 17 Nov
Cosmopolitano Hotel Boutique
A spacious room with a wooden floor and large windows offering a city view.
A buffet table with various food items and a wine bottle.
A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.
A spacious lobby with a grand chandelier, marble flooring, and a statue.

16. Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
Santa Cruz
R2 162
R2 162 total
06 Nov - 07 Nov
Swissôtel Santa Cruz De La Sierra
A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.
A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.
A window seat with a view of a cityscape at dusk.
A spacious lobby with a high ceiling, modern furniture, and a central seating area.

17. Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
Santa Cruz
R2 122
R2 122 total
24 Oct - 25 Oct
Novotel Santa Cruz De La Sierra
Reception
Front of property
Rooftop terrace
Room

18. Hotel Maywa

Hotel Maywa
Santa Cruz
R736
R736 total
19 Oct - 20 Oct
Hotel Maywa
A hotel room with a round wooden table, two single beds, a red chair, and a wooden wall.
A spacious living area with a black sofa, a glass coffee table, and a plant.
A hotel room with a bed, a desk with a computer and two remote controls, a window with a city view, and a wooden headboard.
A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

19. Hotel Pascana centro

Hotel Pascana centro
Centro Histórico
R1 186
R1 186 total
19 Oct - 20 Oct
Hotel Pascana centro
A bedroom with a bed, a desk, and a chair.
A multi-story building with a ground-level commercial space, a visible sign for a rental service, and a parked motorcycle.
A corner of a room with a dark wicker sofa, a matching armchair, and a small ottoman. There are two potted plants on the floor.
A workspace with a laptop, desk lamp, and a standing fan.

20. 518 RENT

518 RENT
Centro Histórico
R185
R267 total
19 Oct - 20 Oct
518 RENT
View all properties

Get last-minute hotel deals in Santa Cruz and save more

Sign in to unlock great savings.
The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.
A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.
A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.
A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Chairú Eco Hotel
Santa Cruz
R848 off
R812
per night
R1 624 total
Chairú Eco Hotel
A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".
A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.
An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.
A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
Equipetrol
R1 661 off
R2 053
per night
R4 106 total
Alfonsina Hotel Boutique by Inboccaluppo
A modern lobby with seating areas, a coffee table, and a large potted plant.
A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.
A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.
A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
Equipetrol
R718 off
R1 050
per night
R2 099 total
Ibis Santa Cruz DE LA Sierra
A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.
A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.
A modern hotel building with a glass facade, a prominent sign for 'OSHO HOTEL', and a logo with a stylized building and tree.
A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

HOTEL OSHO

HOTEL OSHO
Santa Cruz
R482 off
R723
per night
R1 446 total
HOTEL OSHO
Reception
Front of property
Rooftop terrace
Room

Hotel Maywa

Hotel Maywa
Santa Cruz
R164 off
R736
per night
R1 473 total
Hotel Maywa
A spacious lobby with a high ceiling, modern furniture, and a large chandelier.
A breakfast table with plates of food, glasses of juice, and a cup of coffee.
A modern interior with a white sofa, a dining area, and a staircase.
A rooftop bar with a pool, lounge chairs, and a city view.

Hotel Arenal

Hotel Arenal
Centro Histórico
R346 off
R979
per night
R1 958 total
Hotel Arenal
A modern bedroom with a bed, bedside table, and a desk with a laptop.
A modern bathroom with a glass shower, a potted plant, and a towel rack.
A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.
A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

Hotel G

Hotel G
Santa Cruz
R179 off
R507
per night
R1 013 total
Hotel G
A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".
A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.
A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.
A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
Santa Cruz
R99 off
R445
per night
R890 total
Apart Hotel Premium Suites Santa Cruz
A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.
A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.
A buffet with various fruits and snacks.
A sauna with wooden walls and benches.

Hotel Cortez

Hotel Cortez
Equipetrol
R534 off
R2 402
per night
R4 805 total
Hotel Cortez
A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.
A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.
A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.
A modern reception area with a grey reception desk labeled "hola. bienvenido".

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
Santa Cruz
R1 033 off
R939
per night
R1 960 total
Hotel LP Santa Cruz Centro
A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.
A hotel room with two beds, a desk, a television, and a small kitchenette.
A man in a suit entering an elevator.
A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

Hotel Las Américas

Hotel Las Américas
Centro Histórico
R175 off
R786
per night
R1 572 total
Hotel Las Américas
A modern rooftop pool with a city view, wooden flooring, and a seating area.
A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.
A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.
A modern hotel room with a bed, bedside table, and a desk with a chair.

AMERICA APARTMENTS

AMERICA APARTMENTS
Santa Cruz
R128 off
R574
per night
R1 148 total
AMERICA APARTMENTS
A buffet setup with various food items and beverages.
A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.
A corridor with wooden doors, orange walls, and a carpeted floor.
A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

Hotel LP Equipetrol

Hotel LP Equipetrol
Equipetrol
R446 off
R1 262
per night
R2 607 total
Hotel LP Equipetrol
A swimming pool with three people sitting by the edge, one holding a drink.
A buffet setup with various food items and a person serving.
A hotel room with two beds, each with a quilted bedspread, bedside lamps, and a small table with a chair.
A multi-story hotel with a modern facade, large windows, and a prominent sign at the top.

Hotel Continental Park

Hotel Continental Park
Centro Histórico
R1 134
per night
R2 269 total
Sign in for extra savings
Hotel Continental Park
A hotel with a large swimming pool, multiple balconies, and a central arched entrance.
A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.
A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.
A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Sun Hotel
Santa Cruz
R1 735
per night
R3 470 total
Sign in for extra savings
Sun Hotel
A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.
A building with a sign that reads "COSMOPOLITANO."
A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.
A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
Centro Histórico
Cosmopolitano Hotel Boutique
A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".
A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.
An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.
A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
Equipetrol
R1 087 off
R1 796
per night
R1 796 total
Alfonsina Hotel Boutique by Inboccaluppo
A modern lobby with seating areas, a coffee table, and a large potted plant.
A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.
A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.
A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
Equipetrol
Ibis Santa Cruz DE LA Sierra
The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.
A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.
A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.
A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Chairú Eco Hotel
Santa Cruz
R457 off
R779
per night
R779 total
Chairú Eco Hotel
A hotel with a large swimming pool, multiple balconies, and a central arched entrance.
A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.
A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.
A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Sun Hotel
Santa Cruz
R362 off
R1 780
per night
R1 780 total
Sun Hotel
A spacious lobby with a high ceiling, modern furniture, and a large chandelier.
A breakfast table with plates of food, glasses of juice, and a cup of coffee.
A modern interior with a white sofa, a dining area, and a staircase.
A rooftop bar with a pool, lounge chairs, and a city view.

Hotel Arenal

Hotel Arenal
Centro Histórico
R173 off
R979
per night
R979 total
Hotel Arenal
A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.
A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.
A modern hotel building with a glass facade, a prominent sign for 'OSHO HOTEL', and a logo with a stylized building and tree.
A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

HOTEL OSHO

HOTEL OSHO
Santa Cruz
R180 off
R842
per night
R842 total
HOTEL OSHO
A modern bedroom with a bed, bedside table, and a desk with a laptop.
A modern bathroom with a glass shower, a potted plant, and a towel rack.
A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.
A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

Hotel G

Hotel G
Santa Cruz
R194 off
R452
per night
R452 total
Hotel G
Reception
Front of property
Rooftop terrace
Room

Hotel Maywa

Hotel Maywa
Santa Cruz
R82 off
R736
per night
R736 total
Hotel Maywa
A buffet setup with various food items and beverages.
A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.
A corridor with wooden doors, orange walls, and a carpeted floor.
A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

Hotel LP Equipetrol

Hotel LP Equipetrol
Equipetrol
R414 off
R815
per night
R897 total
Hotel LP Equipetrol
A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".
A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.
A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.
A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
Santa Cruz
R49 off
R445
per night
R445 total
Apart Hotel Premium Suites Santa Cruz
A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.
A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.
A buffet with various fruits and snacks.
A sauna with wooden walls and benches.

Hotel Cortez

Hotel Cortez
Equipetrol
R549 off
R2 195
per night
R2 195 total
Hotel Cortez
A spacious room with a wooden floor and large windows offering a city view.
A buffet table with various food items and a wine bottle.
A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.
A spacious lobby with a grand chandelier, marble flooring, and a statue.

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
Santa Cruz
R2 162
per night
R2 162 total
Sign in for extra savings
Swissôtel Santa Cruz De La Sierra
A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.
A hotel room with two beds, a desk, a television, and a small kitchenette.
A man in a suit entering an elevator.
A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

Hotel Las Américas

Hotel Las Américas
Centro Histórico
R48 off
R430
per night
R430 total
Hotel Las Américas
A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.
A spacious lobby with high ceilings, large windows, and a modern chandelier.
A restaurant with a long counter, dark chairs, and hanging lights.
An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

Camino Real Hotel

Camino Real Hotel
Santa Cruz
R3 117
per night
R3 117 total
Sign in for extra savings
Camino Real Hotel

Check out pet-friendly hotels in Santa Cruz

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.
A building with a sign that reads "COSMOPOLITANO."
A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.
A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
Centro Histórico
R871
R871 total
16 Nov - 17 Nov
Cosmopolitano Hotel Boutique
A modern lobby with seating areas, a coffee table, and a large potted plant.
A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.
A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.
A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
Equipetrol
R690
R690 total
24 Oct - 25 Oct
Ibis Santa Cruz DE LA Sierra
A hotel room with a round wooden table, two single beds, a red chair, and a wooden wall.
A spacious living area with a black sofa, a glass coffee table, and a plant.
A hotel room with a bed, a desk with a computer and two remote controls, a window with a city view, and a wooden headboard.
A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

Hotel Pascana centro

Hotel Pascana centro
Centro Histórico
R1 186
R1 186 total
19 Oct - 20 Oct
Hotel Pascana centro
A hotel room with a bed, a desk with a chair, a television, and a window with a city view.
A corridor with tiled flooring, potted plants, and a view of a building with a thatched roof.
A gym with various exercise equipment, including a treadmill, weight machines, and a bench.
A lobby with a marble floor, an elevator, and a view of the outdoor seating area.

Gran Hotel Santa Cruz

Gran Hotel Santa Cruz
Centro Histórico
R961
R961 total
19 Oct - 20 Oct
Gran Hotel Santa Cruz
A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.
A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.
A modern hotel building with a glass facade, a prominent sign for 'OSHO HOTEL', and a logo with a stylized building and tree.
A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

HOTEL OSHO

HOTEL OSHO
Santa Cruz
R832
R832 total
15 Nov - 16 Nov
HOTEL OSHO
A modern rooftop pool with a city view, wooden flooring, and a seating area.
A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.
A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.
A modern hotel room with a bed, bedside table, and a desk with a chair.

AMERICA APARTMENTS

AMERICA APARTMENTS
Santa Cruz
R638
R638 total
19 Oct - 20 Oct
AMERICA APARTMENTS
A buffet setup with various food items and beverages.
A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.
A corridor with wooden doors, orange walls, and a carpeted floor.
A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

Hotel LP Equipetrol

Hotel LP Equipetrol
Equipetrol
R747
R829 total
13 Nov - 14 Nov
Hotel LP Equipetrol
A modern bedroom with a bed, bedside table, and a desk with a laptop.
A modern bathroom with a glass shower, a potted plant, and a towel rack.
A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.
A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

Hotel G

Hotel G
Santa Cruz
R452
R452 total
16 Nov - 17 Nov
Hotel G
A hotel room with two beds, a desk, a chair, a television, and a window with curtains.
A café area with a staircase, a sofa, and tables with chairs.
A wooden door with a notice and a small bedside table with a lamp.
A reception desk with a wooden finish, a framed wildlife painting, and a green leaf-patterned wall mural.

Gran Hotel Mediterráneo

Gran Hotel Mediterráneo
Centro Histórico
R901
R901 total
19 Oct - 20 Oct
Gran Hotel Mediterráneo
A modern hotel room with a bed, a nightstand, a lamp, a painting, a kitchen area, and a bathroom.
A modern kitchen with wooden cabinets, a black countertop, and a built-in stove.
A hotel reception area with a reception desk, a waiting area with a chair and ottoman, and an elevator.
A compact kitchen with a stove, sink, and coffee maker. A bed with a blue pillow is visible in the background.

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
Santa Cruz
R847
R847 total
19 Oct - 20 Oct
Equipetrol Suites Apart Hotel
View all properties

You can also stay at hotels with a pool in Santa Cruz

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.
A building with a sign that reads "COSMOPOLITANO."
A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.
A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
Centro Histórico
R871
R871 total
16 Nov - 17 Nov
Cosmopolitano Hotel Boutique
A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.
A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.
A modern lobby with a dining area, sofas, and a decorative wall.
A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
Santa Cruz
R1 743
R1 743 total
01 Nov - 02 Nov
Marriott Santa Cruz de la Sierra Hotel
A swimming pool with a fountain, surrounded by a wooden deck and palm trees.
A hotel room with two beds, a red textured wall, a framed picture, and a nightstand with a lamp.
A plate of food with a variety of toppings and a glass of wine on a table.
A room with a central decorative object emitting steam, surrounded by dark tiled walls and a tiled floor.

Mora Grande

Mora Grande
Santa Cruz
R1 038
R1 038 total
19 Oct - 20 Oct
Mora Grande
A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".
A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.
An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.
A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
Equipetrol
R1 796
R1 796 total
30 Oct - 31 Oct
Alfonsina Hotel Boutique by Inboccaluppo
A hotel room with a round wooden table, two single beds, a red chair, and a wooden wall.
A spacious living area with a black sofa, a glass coffee table, and a plant.
A hotel room with a bed, a desk with a computer and two remote controls, a window with a city view, and a wooden headboard.
A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

Hotel Pascana centro

Hotel Pascana centro
Centro Histórico
R1 186
R1 186 total
19 Oct - 20 Oct
Hotel Pascana centro
A poolside area with lounge chairs and a palm tree.
A pathway through a lush garden with various trees and shrubs.
A dining table with breakfast items and a pool view.
A banquet hall with long tables, chandeliers, and draped curtains.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Equipetrol
R2 227
R2 227 total
07 Nov - 08 Nov
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
A hotel room with a bed, a desk with a chair, a television, and a window with a city view.
A corridor with tiled flooring, potted plants, and a view of a building with a thatched roof.
A gym with various exercise equipment, including a treadmill, weight machines, and a bench.
A lobby with a marble floor, an elevator, and a view of the outdoor seating area.

Gran Hotel Santa Cruz

Gran Hotel Santa Cruz
Centro Histórico
R961
R961 total
19 Oct - 20 Oct
Gran Hotel Santa Cruz
A hotel with a large swimming pool, multiple balconies, and a central arched entrance.
A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.
A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.
A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Sun Hotel
Santa Cruz
R1 780
R1 780 total
19 Oct - 20 Oct
Sun Hotel
A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.
A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.
A window seat with a view of a cityscape at dusk.
A spacious lobby with a high ceiling, modern furniture, and a central seating area.

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
Santa Cruz
R2 122
R2 122 total
24 Oct - 25 Oct
Novotel Santa Cruz De La Sierra
A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.
A modern lobby with wooden paneling, two grey sofas, and pendant lighting.
A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.
A modern staircase with glass railings, leading to a landing with a small garden area.

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
Santa Cruz
R758
R758 total
20 Oct - 21 Oct
Premium Suites Deluxe Aparthotel Equipetrol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveller single night rates
View properties in October
Typical weather for Santa Cruz
October
High 32°C / low 22°C. Sunny most days.
View properties in October
32°
22°
32°
22°
31°
22°
31°
22°
29°
22°
29°
21°
28°
20°
25°
18°
24°
17°
25°
17°
28°
18°
31°
21°
Monthly weather averages (˚C)

Top neighbourhoods in Santa Cruz

Equipetrol

Santa Cruz's Equipetrol neighbourhood offers attractions, including Santa Cruz Zoo.

Centro Histórico

Santa Cruz's Centro Histórico neighbourhood is home to attractions, such as Plaza 24 de Septiembre and La Recova Artisan Walk.

Top landmarks in Santa Cruz

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
If you're planning a bit of sightseeing, head to Plaza 24 de Septiembre – just one of the monuments in Centro Histórico.
See properties
A historic tower with a clock, surrounded by lush greenery and palm trees.

San Lorenzo Cathedral

9.0/10 (84 reviews)
Centro Histórico is home to San Lorenzo Cathedral, so why not stop by during your stay in Santa Cruz?
See properties

Ventura Mall

9.0/10 (183 reviews)
If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.
See properties

Guembe Biocenter

8.8/10 (60 reviews)
Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs a little more? Head to Arenal Park, located nearby.
See properties

Santa Cruz Zoo

8.4/10 (53 reviews)
It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a visit to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Franco Aleman Cultural Center, both located nearby.
See properties

Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)
You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.
See properties

Blacutt Square

8.2/10 (19 reviews)
You might want to get your camera out and head to Blacutt Square – just one of the landmarks located 0.7 mi (1.1 km) from central Santa Cruz.
See properties

Cine Center

8.0/10 (53 reviews)
Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay? If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.
See properties

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Ethno-folkloric Museum and Cine Center.

See all hotels in Santa Cruz
A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Check out reviews of Santa Cruz hotels guests love

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent
"Perfect place while in Santa Cruz! Comfortable and relaxed setting. 100%"
William 1-night trip
Posted 2 hours ago
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hotel Las Américas

Hotel Las Américas

10/10 Excellent
"All"
Silvia 2-night trip
Posted 1 day ago
Hotel Las Américas
Hotel Cortez

Hotel Cortez

10/10 Excellent
"El hotel es fantastico, el desayuno excelente, los servicios que brinda el hotel son un plus para el huésped. En general, el personal es atento y amable. Sin embargo, tuvimos problemas en el check in, la señorita que nos recibió indicó que no teníamos reservación. Se le indicó que la reservación se había hecho por Expedia y ella insistió en que no teníamos alguna. Cuando llamé a Expedia, nos dijo que, aunque el hotel estaba lleno, nos darían una habitación. Esta señorita parece no ser tan amable, lo cual es la excepción, pues el personal es atento y presto a ayudar al huésped."
LILLIAN 6-night trip
Posted 2 days ago
Hotel Cortez
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

10/10 Excellent
"Muy buen servicio"
Janeiro 4-night trip
Posted 5 days ago
TRYP by Wyndham Santa Cruz
Chairú Eco Hotel

Chairú Eco Hotel

8/10 Good
"The breakfast was not that good, but everything was good"
Olga Lidia 2-night trip
Posted 3 weeks ago
Chairú Eco Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
Scott 7-night trip
Posted 2 months ago
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent
"All around good price and location"
Alejandro 1-night trip
Posted 2 months ago
Novotel Santa Cruz De La Sierra
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

10/10 Excellent
"Todo muy bien"
lady 2-night trip
Posted 2 months ago
Delfines Collection Hotel By Mercure
Hotel LP Equipetrol

Hotel LP Equipetrol

8/10 Good
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"
José Bernardo 1-night trip
Posted 4 months ago
Hotel LP Equipetrol

Frequently asked questions

Can I book a refundable accommodation option in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most hotels offer refundable* rates that you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santa Cruz if I want a holiday rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 23 holiday homes. In addition, you can choose from 198 apartments.
What will the weather in Santa Cruz be like during my visit?
Santa Cruz is a great place to visit to enjoy the sunshine at any time of year, with an average temp of 21°C.
Why should I book my Santa Cruz hotel with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Find out more about Santa Cruz

Santa Cruz: A Vibrant Tapestry of Nature's Blooms and Architectural Wonders

Nestled in the heart of Bolivia, Santa Cruz captivates with its vibrant cityscape, lush floral displays, and the majestic Cathedral that graces its skyline. Embracing Bolivian hospitality, visitors can savour the charm of central Santa Cruz and its rich cultural heritage, making it a perfect destination for a memorable next stay. Experience the blend of modern life and traditional splendour in this dynamic city.

Discover great hotels near Santa Cruz

Santa Cruz, Santa Cruz, Bolivia offers a range of hotels from cosy, comfortable stays to luxurious options, often rated up to five stars. Ideal accommodations come with modern amenities, welcoming lounges and elegant dining areas, ensuring a pleasant stay for travellers. Here are some of the most popular hotels with our travelers near Santa Cruz:

  1. Hotel Rio Selva Resort Santa CruzOpens in a new window: This 3.0-star hotel offers travellers a comfortable and inviting experience, highlighted by its thoughtfully curated amenities for children including a free crib, shared playground, supervised childcare on site, a child-friendly pool, and on-site babysitting childcare. Ideal for leisure travellers seeking a relaxed and family-friendly retreat, the property provides a welcoming atmosphere and smooth service throughout your stay.
  2. Novotel Santa Cruz De La SierraOpens in a new window: This 5.0-star hotel boasts an impressive guest rating and a luxurious setting tailored for leisure travellers. Guests can indulge in high-end experiences with standout features such as a rooftop bar, spa, infinity pool, express check-in, and curated high-quality amenities. The property offers an atmosphere of elegant design and premium comfort, ensuring a distinctive and memorable journey.
  3. Marriott Santa Cruz de la Sierra HotelOpens in a new window: This 5.0-star hotel, with an outstanding guest rating, dazzles leisure travellers with its luxurious and boutique ambiance. Highlighting a range of curated experiences, guests can enjoy high-end offerings such as an infinity pool, rooftop bar, spa, high-end restaurant, and express check-in. The property exudes a refined architectural design and a smooth service, promising a journey filled with premium comfort and top-tier amenities.

4 tips for savvy savings when booking a hotel in Santa Cruz

  1. Book for the cheapest times: The most affordable time to visit Santa Cruz is from June to August, when hotel prices are lower. For an enriching experience, it's recommended to stay for at least 3 to 4 days to thoroughly enjoy the city's key landmarks and cultural sites. During your visit, you can explore charming cafes, indulge in shopping, admire the local flora, visit the zoo, and partake in excursions centred around the area's history. Additionally, there are opportunities for birdwatching and enjoying local soccer matches, all of which provide great value for money while travelling on a budget. As a bonus, prices may drop during this period, making it an even more budget-friendly option for your getaway.
  2. Look for last-minute deals on Hotels.com: To discover last-minute deals to Santa Cruz, visit the DealsOpens in a new window or Last-Minute Deals section on Hotels.com, where you may find discounted hotel options as your travel date approaches. You could also enable email alerts or push notifications from Hotels.com to stay updated on flash sales and exclusive promotions, helping you seize any opportunities to save. Additionally, Smart Shopping is a useful tool within the app that allows you to compare hotel prices and amenities, ensuring you’re informed if prices drop or rooms become available, making your last-minute getaway even more accessible.
  3. Be flexible with dates: Prices may vary depending on factors such as the hotel's location, star rating, and time of year, so remaining flexible with your dates could help you save on your stay in a Santa Cruz hotel. For those seeking unique experiences, boutique hotels may offer a more personalised experience and occasionally better value. When you book with Hotels.com, we will inform you if the price for your selected dates is above or below the average, and if it appears to be on the higher side, we might suggest more affordable dates to help you find a better deal.
  4. Consider your location: Hotels situated near the city centre generally tend to be more expensive, but with Santa Cruz's excellent public transport connections, you may discover a more affordable independent hotel further afield that remains well-connected. For those keen to explore alternative, less crowded neighbourhoods or even lesser-known nearby towns, there is often great value for money to be found. Opting for these alternative destinations could provide a more authentic and budget-friendly experience.

Best time to go to Santa Cruz

Santa Cruz experiences its lowest average temperature in June, at 67.8°F (19.9°C), while October is the hottest month, with an average temperature of 79.5°F (26.4°C). January is typically the wettest month. If you’re looking to soak up the lively atmosphere in Santa Cruz, January, July, and September are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is sunny to mostly sunny, with little to no rainfall. However, if you prefer a more relaxed experience, May, October, and December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.

Keep exploring