Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Santa Cruz on Hotels.com. These Santa Cruz hotels consistently deliver on comfort, location and traveller experience. Last updated on .
Hotels & Accommodation in Santa Cruz
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Top 5 hotels in Santa Cruz at a glance
- 1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel — 3.5-star hotel in Santa Cruz. Guest rating: 9,0/10 — Wonderful.
- 2. Camino Real Hotel — 4.5-star hotel in Santa Cruz. Guest rating: 9,0/10 — Wonderful.
- 3. Hotel Cortez — 3.5-star hotel in Santa Cruz. Guest rating: 9,4/10 — Exceptional.
- 4. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia — 4.5-star hotel in Santa Cruz. Guest rating: 9,2/10 — Wonderful.
- 5. Hotel LP Equipetrol — 3.5-star hotel in Santa Cruz. Guest rating: 8,2/10 — Very good.
Where to stay in Santa Cruz?




1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel



2. Camino Real Hotel
Camino Real Hotel



4. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia



5. Hotel LP Equipetrol
Hotel LP Equipetrol



6. Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA Sierra



7. Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel Equipetrol



8. Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel



9. Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra



11. TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa Cruz



13. Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La Sierra



15. Delfines Collection Hotel By Mercure
Delfines Collection Hotel By Mercure



17. Cosmopolitano Hotel Boutique
Cosmopolitano Hotel Boutique



18. Equipetrol Suites Apart Hotel
Equipetrol Suites Apart Hotel



20. Alfonsina Hotel Boutique by Inboccaluppo
Alfonsina Hotel Boutique by InboccaluppoGet last-minute hotel deals in Santa Cruz and save more
Check out pet-friendly hotels in Santa Cruz




Surbackpackers
SurbackpackersYou can also stay at hotels with a pool in Santa Cruz




Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelGo beyond your typical stay in Santa Cruz
Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Top neighbourhoods in Santa Cruz
Top landmarks in Santa Cruz

Plaza 24 de Septiembre

San Lorenzo Cathedral
Ventura Mall
Guembe Biocenter
Santa Cruz Zoo
Cine Center
Ramon Tahuichi Aguilera Stadium
Lomas de Arena Regional Park
Learn more about Santa Cruz
Santa Cruz is applauded for its cultural attractions such as Cine Center and Ethno-folkloric Museum.
See all hotels in Santa Cruz
Check out reviews of Santa Cruz hotels guests love
Hotel Cortez
"Great place. Safe, clean, attractive everything u could want"
Ibis Santa Cruz DE LA Sierra
"Buen hotel Limpio y comodo"
Sun Hotel
"Breakfast was excellent!"
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
"Great breakfast and beautiful property. Would come here again. Felt safe and comfortable."
Delfines Collection Hotel By Mercure
"Todo muy bien"
Hotel LP Equipetrol
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"
Alfonsina Hotel Boutique by Inboccaluppo
"Good hotel. Very contemporary; buffet breakfast included. We walked to the old part of the city/cathedral - probably about 40 minutes walk but can stop for a coffee along the way! Restaurant and bar in hotel. Hotel also close to many other restaurants/bars"
Apart Hotel Premium Suites Santa Cruz
"Great location."
Frequently asked questions
Find out more about Santa Cruz
Santa Cruz: A Vibrant Tapestry of Nature's Blooms and Architectural Wonders
Nestled in the heart of Bolivia, Santa Cruz captivates with its vibrant cityscape, lush floral displays, and the majestic Cathedral that graces its skyline. Embracing Bolivian hospitality, visitors can savour the charm of central Santa Cruz and its rich cultural heritage, making it a perfect destination for a memorable next stay. Experience the blend of modern life and traditional splendour in this dynamic city.
Discover great hotels near Santa Cruz
Santa Cruz, Santa Cruz, Bolivia offers a range of hotels from cosy, comfortable stays to luxurious options, often rated up to five stars. Ideal accommodations come with modern amenities, welcoming lounges and elegant dining areas, ensuring a pleasant stay for travellers. Here are some of the most popular hotels with our travelers near Santa Cruz:
- Hotel Rio Selva Resort Santa CruzOpens in a new window: This 3.0-star hotel offers travellers a comfortable and inviting experience, highlighted by its thoughtfully curated amenities for children including a free crib, shared playground, supervised childcare on site, a child-friendly pool, and on-site babysitting childcare. Ideal for leisure travellers seeking a relaxed and family-friendly retreat, the property provides a welcoming atmosphere and smooth service throughout your stay.
- Novotel Santa Cruz De La SierraOpens in a new window: This 5.0-star hotel boasts an impressive guest rating and a luxurious setting tailored for leisure travellers. Guests can indulge in high-end experiences with standout features such as a rooftop bar, spa, infinity pool, express check-in, and curated high-quality amenities. The property offers an atmosphere of elegant design and premium comfort, ensuring a distinctive and memorable journey.
- Marriott Santa Cruz de la Sierra HotelOpens in a new window: This 5.0-star hotel, with an outstanding guest rating, dazzles leisure travellers with its luxurious and boutique ambiance. Highlighting a range of curated experiences, guests can enjoy high-end offerings such as an infinity pool, rooftop bar, spa, high-end restaurant, and express check-in. The property exudes a refined architectural design and a smooth service, promising a journey filled with premium comfort and top-tier amenities.
4 tips for savvy savings when booking a hotel in Santa Cruz
- Book for the cheapest times: The most affordable time to visit Santa Cruz is from June to August, when hotel prices are lower. For an enriching experience, it's recommended to stay for at least 3 to 4 days to thoroughly enjoy the city's key landmarks and cultural sites. During your visit, you can explore charming cafes, indulge in shopping, admire the local flora, visit the zoo, and partake in excursions centred around the area's history. Additionally, there are opportunities for birdwatching and enjoying local soccer matches, all of which provide great value for money while travelling on a budget. As a bonus, prices may drop during this period, making it an even more budget-friendly option for your getaway.
- Look for last-minute deals on Hotels.com: To discover last-minute deals to Santa Cruz, visit the DealsOpens in a new window or Last-Minute Deals section on Hotels.com, where you may find discounted hotel options as your travel date approaches. You could also enable email alerts or push notifications from Hotels.com to stay updated on flash sales and exclusive promotions, helping you seize any opportunities to save. Additionally, Smart Shopping is a useful tool within the app that allows you to compare hotel prices and amenities, ensuring you’re informed if prices drop or rooms become available, making your last-minute getaway even more accessible.
- Be flexible with dates: Prices may vary depending on factors such as the hotel's location, star rating, and time of year, so remaining flexible with your dates could help you save on your stay in a Santa Cruz hotel. For those seeking unique experiences, boutique hotels may offer a more personalised experience and occasionally better value. When you book with Hotels.com, we will inform you if the price for your selected dates is above or below the average, and if it appears to be on the higher side, we might suggest more affordable dates to help you find a better deal.
- Consider your location: Hotels situated near the city centre generally tend to be more expensive, but with Santa Cruz's excellent public transport connections, you may discover a more affordable independent hotel further afield that remains well-connected. For those keen to explore alternative, less crowded neighbourhoods or even lesser-known nearby towns, there is often great value for money to be found. Opting for these alternative destinations could provide a more authentic and budget-friendly experience.
Best time to go to Santa Cruz
Santa Cruz experiences its lowest average temperature in June, at 67.8°F (19.9°C), while October is the hottest month, with an average temperature of 79.5°F (26.4°C). January is typically the wettest month. If you’re looking to soak up the lively atmosphere in Santa Cruz, January, July, and September are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is sunny to mostly sunny, with little to no rainfall. However, if you prefer a more relaxed experience, May, October, and December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.
















































































































