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Sister Islands Hotels, Cayman Islands

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  • Free cancellation on most rooms
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Intro to Sister Islands hotels and accommodations

Going on holiday to Sister Islands? Hotels.com has the right accommodation for you.
It is one of the most beautiful places in Cayman Islands and on Hotels.com you will find a wide range of accommodation in many cities of this region.

Use our search function to filter and compare the hotels and find the right place for your stay. From 5 stars hotels to cheap hotels you will find the most suitable accommodation for your stay.
You will be able to sort your results per:
  • Nightly rates/ price
  • Location within Sister Islands
  • Cities in Sister Islands
  • Top attractions in Sister Islands
  • Hotels in different areas of Cayman Islands
  • Genuine Hotels.com guest reviews for each hotel in Sister Islands
  • Star rating
  • Amenities
  • Hotel name & chain
  • Theme (business, luxury, romantic...)
When you book your stay in Sister Islands with Hotels.com you may also earn free nights on participating hotels by joining the Hotels.com Rewards programme.
It's free to join and only takes 2 minutes to sign up and when you stay 10 nights you receive 1 night free*. So even a short weekend break in Sister Islands can get you on your way to a free night.

As well as our Hotels.com guest reviews, we also display Expedia reviews for hotels and also the TripAdvisor review score for each of our hotels in Sister Islands.
And when you make a hotel reservation in Sister Islands with Hotels.com we'll send you a confirmation with the reservation details of your Sister Islands hotel booking along with contact details, directions, information about nearby attractions, restaurants and even the weather.
To make the most of our service, download our mobile & tablet apps and sign up to our newsletter and follow us on Facebook, Google+ and Twitter to receive the latest Sister Islands deals and Hotels.com discount codes.

Collect 10 nights get 1 free*

And look out for Secret Prices on selected properties