Hotels & Accommodation in St. Charles

Search for accommodation in St. Charles

Hotels.com™ Rewards

Collect 10 nights, get 1 reward night

And look out for Secret Prices on selected hotels

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Discover St. Charles

Visitors to St. Charles speak favorably about this family-friendly city's casinos, historical sites, and restaurants. You'll enjoy the area's live music, theater, and sporting events. You can take in the local culture of St. Charles at Lewis & Clark Boathouse and Nature Center and Weldon Spring Site Interpretive Center. While you're here, stop by First Missouri State Capitol Historic Site and Katy Trail.